Eplerenone Improved Hypokalemia in a Patient with Gitelman's Syndrome

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Eplerenone improved hypokalemia in a patient with Gitelman's syndrome.

A 47-year-old woman presented with hypokalemia (2.4 mmol/L). She also had hypomagnesemia, hypocalciuria, and hyperreninemic hyperaldosteronism. Sequence analysis revealed a compound heterozygous mutation, R655C and R955Q, in the SLC12A3 gene. These findings were compatible with Gitelman's syndrome (GS). Eplerenone, a selective aldosterone blocker, in combination with oral potassium chloride imp...

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ژورنال

عنوان ژورنال: Internal Medicine

سال: 2012

ISSN: 0918-2918,1349-7235

DOI: 10.2169/internalmedicine.51.5723